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Influence of Polarization Setting on Gold Nanorod Signal at Nonplasmonic Wavelengths Under Differential Interference Contrast Microscopy

TitleInfluence of Polarization Setting on Gold Nanorod Signal at Nonplasmonic Wavelengths Under Differential Interference Contrast Microscopy
Publication TypeJournal Article
Year of Publication2012
AuthorsStender AS, Augspurger AE, Wang GF, Fang N
Journal TitleAnalytical Chemistry
Volume84
Pages5210-5215
Date Published06
Type of ArticleArticle
ISBN Number0003-2700
Accession NumberWOS:000305320500009
Abstract

Researchers rely on a variety of microscopic techniques for observing and tracking anisotropic nanoparticles in real time experiments. This technical note focuses on the optical behavior exhibited by gold nanorods at nonplasmonic wavelengths under differential interference contrast microscopy (DIC). Intense diffraction patterns appear at nonplasmonic wavelengths, and the behavior of these patterns can be altered by adjusting the surrounding medium or the polarizer setting. Such patterns are absent when linear and crossed polarizations are utilized. Making polarization adjustments is important in DIC microscopy, because it affects bias retardation and image contrast. The nonplasmonic diffraction bands that were observed could potentially be exploited for rotational tracking, but more importantly, researchers should exhibit care in selecting a nanorod sample and the polarization setting when working with DIC microscopy.
URL<Go to ISI>://WOS:000305320500009http://pubs.acs.org/doi/pdfplus/10.1021/ac301072f
DOI10.1021/ac301072f
Alternate JournalAnal. Chem.