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Fluorescent Polystyrene-Fe3O4 Composite Nanospheres for In Vivo Imaging and Hyperthermia

TitleFluorescent Polystyrene-Fe3O4 Composite Nanospheres for In Vivo Imaging and Hyperthermia
Publication TypeJournal Article
Year of Publication2009
AuthorsShi DL, Cho HS, Chen Y, Xu H, Gu HC, Lian J, Wang W, Liu GK, Huth C, Wang LM, Ewing RC, Budko S, Pauletti GM, Dong ZY
Journal TitleAdvanced Materials
Volume21
Pages2170-+
Date PublishedJun 5
ISBN Number0935-9648
Accession NumberISI:000267308800006
Keywordsalternating magnetic-field, diagnostics, live cells, nanoparticles, semiconductor quantum dots, time
Abstract

Quantum dots (QDs) are immobilized on the surfaces of magnetic Fe3O4-composite nanospheres (MNSs, see figure). The QDs exhibit intense visible-light emission in fluorescence spectroscopy and successfully facilitate, for the first time, in vivo soft-tissue imaging in live mice. The Fe3O4 nanoparticles respond to an external magnetic field by increasing the temperature of the surrounding environment (i.e., hyperthermia), which can be used therapeutically.
URL<Go to ISI>://000267308800006
DOI10.1002/Adma.200803159